Abstract

A real-time RF exposure setup for studying the mechanism of RF biological effects based on microelectrode array (MEA) is proposed in this letter. The reflection simulation and measurement of the exposure setup show that the exposure setup has a wide working bandwidth in the frequency range of dc-3.0 GHz. The specific adsorption rate (SAR) measurement and simulation results at some frequencies show that the SAR distributions in the electrode region are relatively uniform. The test of the real-time effects on neuron activities at the SAR of 2.2 W/kg with a continuous 2.45-GHz RF signal injection was carried out. The results show that most of the electrodes can work normally and will not be affected by electromagnetic field noise. Additionally, the setup is compact and the system with MEA platform is almost covered by metal, which would significantly improve the ability to isolate the internal and external electromagnetic waves.

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