Abstract
Data from ovarian hyperstimulation cycles suggest that follicle stimulating hormone (FSH) action is modulated by a frequent polymorphism of the FSH receptor gene exchanging Asn to Ser at codon 680. Women homozygous for the Ser680 variant, display an attenuated FSH receptor function. We hypothesized, that the FSH receptor genotype influences also the normal, ovulatory menstrual cycle, with different ovarian and hormonal dynamics.
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