Abstract
In this commentary, it is presented how the Ascona B-DNA (ABC) consortium analyses of the DNA structure and deformability had a great influence in the development of mesoscopic models of DNA. The generation of databases using molecular dynamics ensembles to describe the DNA flexibility, allowed mesoscopic models to improve and become more accurate with a quality similar to that of all-atom MD simulations. All this will be translated in the future in the development of mesoscopic methods that could study and reproduce large biological systems such as chromatin structure, nucleosome arrangements, and protein recognition.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
