Abstract
Cyclic regeneration of the co-enzyme nicotinamide adenine dinucleotide couple NAD+/NADH has been achieved by reduction of NAD+ using electrochemically produced potassium amalgam in a specially designed reactor, and by electrochemically oxidising NADH and biochemically inactive species from the reduction reaction back to active NAD+via a nickel foam anode; this regenerated co-enzyme can be used to drive a range of chemical reactions catalysed by oxido–reductase enzymes.
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