Abstract

A cohort study: Myocardial infarction with non-obstructive coronary arteries (MINOCA) in an Irish tertiary centre

Highlights

  • Acute myocardial infarction with unobstructed (≤ 50% stenosis) coronary arteries (MINOCA) has a prevalence of approximately 10% of patients with suspected myocardial infarction [1,2]

  • Of a total of 146 patients admitted to the University Hospital Limerick with suspected ACS between September 2015 and January 2016, 80 presented as a ST elevation MI (STEMI) while 66 presented as a non-ST elevation MI (NSTEMI)

  • Our study showed a higher incidence of NSTEMI patients 73% (n=19) than STEMI findings 27% (n = 7)

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Summary

Introduction

Acute myocardial infarction with unobstructed (≤ 50% stenosis) coronary arteries (MINOCA) has a prevalence of approximately 10% of patients with suspected myocardial infarction [1,2]. MINOCA remains a serious concern due to the uncertain risk of major adverse coronary events (MACE) during follow-up. The management of AMI has evolved with troponin values, changes on electrocardiogram, early use of coronary angiography and reperfusion therapies forming the foundation of contemporary AMI management guidelines. In this context, the European Society of Cardiology recommends following three criteria for the diagnosis of MINOCA [3]. Positive cardiac biomarker such as Troponin with at least one value above the 99th percentile upper reference limit

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