Abstract
Results We assessed data from 64 patients (of which 27 were males 42%) with a median age of 54±14 (range: 23 to 64 years). The median fibrosis was 0.44±0.23 and the median necroinflammatory activity was 0.54±0.24. The median FIB-4 score was 1.89±3.23 at the second visit versus 1.26±2.07 at the third visit. The median APRI score was 1.18±1.67 at the second visit compared to 1.79 ±2.53 at the third visit (p=0.05, 95%CI: 0.0389, 0.43681). Regression analysis showed a correlation between FibroTest (considered the gold standard in this study, in the absence of histology data from liver biopsy), FIB-4 (p=0.43) and APRI (p=0.011).
Highlights
Given the important role played by hepatitis viruses in the development of liver fibrosis we consider it necessary to evaluate markers of disease progression and instruments for staging of fibrosis in patients coinfected with hepatitis B and D viruses (HBV, HDV)
The median APRI score was 1.18±1.67 at the second visit compared to 1.79 ±2.53 at the third visit (p=0.05, 95%CI: 0.0389, 0.43681)
Regression analysis showed a correlation between FibroTest, FIB-4 (p=0.43) and APRI (p=0.011)
Summary
A cohort study in the assessment of liver fibrosis and markers of disease progression in hepatitis B and D coinfection. Tamer Samir Al Aker1*, Oana Streinu-Cercel, Anca Streinu-Cercel, Liliana Lucia Preoțescu, Alina Cristina Neguț, Adrian Streinu-Cercel. From The 9th Edition of the Scientific Days of the National Institute for Infectious Diseases Prof Dr Matei Bals Bucharest, Romania.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
