Abstract
In April 2012, a cluster of two cases of meningococcal disease caused by rifampicin-resistant C meningococci was reported in the Champagne-Ardenne region, France. The two cases occurred in a student population living in the same town but studying at different schools. Bacteriological and epidemiological investigations of cases have shown that the isolates of both cases were non-differentiable.
Highlights
Neisseria meningitidis is a strictly human bacterium encountered in the pharynx in about 10% of the general population [1]
Chemoprophylactic treatment with rifampicin is useful in preventing secondary cases among close contacts of a patient with invasive meningococcal disease (IMD) and in stopping the spread of pathogenic N. meningitidis
According to the annual report of the National Reference Center for Meningococci (NRCM) in Paris, the incidence of rifampicin-resistant meningococci isolated in France averages one per year with no expansion of these isolates and no secondary case [11]
Summary
Citation style for this article: Mounchetrou Njoya I, Deghmane AE, Taha MK, Isnard H, Parent du Châtelet I. A cluster of meningococcal disease caused by rifampicin-resistant C meningococci in France, April 2012. In April 2012, a cluster of two cases of meningococcal disease caused by rifampicin-resistant C meningococci was reported in the Champagne-Ardenne region, France. The two cases occurred in a student population living in the same town but studying at different schools. Bacteriological and epidemiological investigations of cases have shown that the isolates of both cases were non-differentiable
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