Abstract

Breast cancer is a malignant tumor that commonly metastasizes to bones, but not a few long survivors can be seen after bone metastasis occurs. Appropriate selection of therapies would afford an improvement in the patient's quality of life and an effect of life-prolongation, and hence we should be careful to deal with such patients. Of 540 patients with primary breast cancer treated at the hospital in a recant 26-year period since 1971, 60 patients experienced bone metastasis were subjected to study of clinicopathological prognostic factors. As a result, patients with breast cancer who were liable to have bone metastasis had: (1) small tumor with solid-tubular carcinoma or scirrhous carcinoma, (2) papillotubular carcinoma with tumor lenge, and (3) n0 and negative vascular invasion with solid-tubular carcinoma. The patients with solid-tubular carcinoma had easily bone metastasis, but they were found the foci in an early stage and lived for a long time after bone metastasis occurred. It is necessary to examine carefully about bone metastasis for the patients with above mentioned, especially within 5 years after operation.

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