A CLINICOPATHOLOGICAL STUDY ON RESECTED CASES OF CARCINOMA OF THE PANCREAS

Abstract

Among 28 resected cases of carcinoma of the pancreas, 24 excepting 4 death cases due to operation or other diseases were clinicopathologically studied. The 24 patients could be classified by macroscopical staging as 6 in stage II, 11 in stage III, and 7 in stage IV. Histologically there were 13 curative resection and 11 noncurative resection cases.In 13 histologically curative cases one-, 3- or 5-year survival rate was 50%, 37.5%, or 37.5%, respectively. While 11 noncurative cases included no survivals longer than 23 months, and the one-year survival rate was 21.8%. When compared with long survival cases for histological type, moderately differentiated tubular adenocarcinoma appeared predominant in cancer-deaths within one year and noncurative resection cases. As to histological tumor extension, both two long survivers had sa, rpa, n(-), and pv0v0; cancer-deaths were positive against all factors excepting pv; and noncurative resection cases tended to have an extrapancreatic extension. Four of 6 curative resection cases were found to have liver metastasis by necropsy, which indicated that the important factor for long survival might lie on active approach to prevent the liver from metastasizing.