A CLINICOPATHOLOGICAL STUDY ON GASTRIC CANCER WITH ESOPHAGEAL INVASION IN THE CARDIAC REGION

Abstract

One hundred and thirty-one gastric cancers in the cardiac region surgically treated at the department from 1980 to 1992 were classified into two groups: CE-cancers and C-cancers. In this study the clinicopathological charactaristics and therapeutic results of them were studied. Among the clinicopathological charactaristics, there were significant differences between them in gross type of the tumor, tumor size, microscopic depth, vessel invasion, microscopic lymph node metastasis, infiltrative growth, and microscopic stage. These findings suggest that there were more advanced cases in CE-cancers than C-cancers. Curative resection rate was significantly higher in C-cancers, and cummulative five-years survival rate was better in C-cancers (64.1%) than CE-cancers (34.8%). Cummulative survival rate of CE-cancers was studied in length of esophageal invasion, length of oral width, lymph node metastasis, tumor size, and microscopic depth. It was suggested that the grade of lymph node metastasis chiefly affected the prognosis of CE-cancers.