Abstract

Background: To evaluate tumors involving major and minor salivary glands, histopathology is an essential diagnostic method and is the gold standard. This study was carried out to know the incidence of salivary gland tumors, their clinical presentation and diverse morphological patterns. Materials and Methods: A prospective cross-sectional descriptive study was carried out over a period of two years in the department of pathology, Yenepoya Medical College hospital, Mangalore.Data regarding patient demographicswas also recorded. All the epithelial salivary gland tumors were classified according toWHO (2005) histological classification. Results: In the present study, a total of 65 cases of salivary gland tumours was found and an age range of 10-79 years was observed. The most common site affected was the parotid gland 47 (72.31%). Among the 48 (73.85%) benign tumors, pleomorphic adenoma 40 (61.54 %) was most commontumor and remaining 17(26.15%) cases were malignant, of which mucoepidermoid carcinoma 8 (12.31%) was frequently observed. Conclusion: This study highlights the usefulness of histopathologicalstudy of salivary gland tumors with various morphological patterns of benign and malignant salivary gland tumors, which are of utmost value in planning the further management of the patient.

Highlights

  • Salivary gland tumors show diverse morphological patterns between various tumor types and on rare occasions with in the same tumor, causing interpretation challenges among the pathologists [1].Studies from different countries have shown geographic variations in the relative incidence andclinicopathological discrepancies between benign and malignant salivary gland tumors [2]

  • A total of65specimens of salivary gland tumors werereceived during the study period of which, 48 (73.84%) were benign tumors and 17 (26.15 %) were malignant tumors

  • A single case of acinic cell carcinoma was seen in 45 year female, accounting for 1.54% of all tumor slocated in parotid gland which was similar to the findings reported in literature [1,12]

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Summary

Introduction

Salivary gland tumors show diverse morphological patterns between various tumor types and on rare occasions with in the same tumor, causing interpretation challenges among the pathologists [1]. Studies from different countries have shown geographic variations in the relative incidence andclinicopathological discrepancies between benign and malignant salivary gland tumors [2]. This study was carried out to know the incidence of salivary gland tumors, their clinical presentation and diverse morphological patterns. Materials and Methods: A prospective cross-sectional descriptive study was carried out over a period of two years in the department of pathology, Yenepoya Medical College hospital, Mangalore.Data regarding patient demographicswas recorded.All the epithelial salivary gland tumors were classified according toWHO (2005) histological classification. Results: In the present study, a total of 65 cases of salivary gland tumours was found and an age range of 10-79 years was observed. Conclusion: This study highlights the usefulness of histopathologicalstudy of salivary gland tumors with various morphological patterns of benign and malignant salivary gland tumors, which are of utmost value in planning the further management of the patient

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