A Clinicopathological Study of Salivary Gland Lesions and Immunohistochemical Expression of Bcl2 in Benign and Malignant Salivary Gland Neoplasms

Abstract

Introduction Salivary glands neoplasms (SGNs) are rare tumors and comprise approximately 3-10% of the neoplasms of the head and neck region and 1% of the neoplasms of the whole body(1) . Annual global incidence of SGNs is between 0.4 to 13.5 cases per 1, 00,000 individuals(2) . Among these, malignant salivary gland neoplasms (MSGNs) are 0.40 to 0.65 per 1, 00,000 cases(3) . MSGNs are 0.3% of all malignancies(4) . Early diagnosis of MSGNs play an important role in better management of these tumors(5) . Fine-needle aspiration cytology (FNAC) is used as a screening and early diagnostic tool in SGNs however its role is limited(6) . Accurate diagnosis depends upon the histological evaluation of SGNs