A CLINICOPATHOLOGICAL STUDY OF NON NEOPLASTIC AND NEOPLASTIC BREAST DISEASES AND ITS CORRELATION WITH RADIOLOGICAL DIAGNOSIS

Abstract

Objectives- 1) To study the various modes of clinical presentation, etio-pathogenesis of non- neoplastic and neoplastic breast diseases. 2) Comparing with the FNAC and radiological diagnosis. Methods- 60 female patients with lump in the breast were taken for the study. After clinical diagnosis it was cross checked with radiological diagnosis and FNAC. The excised specimen was sent for Histopathological examination and results were compared with clinical diagnosis, cytological diagnosis, and radiological diagnosis. Accuracy and predictive values were calculated out of the results. Results: Out of 60 patients, 39(65%) breast lumps were benign & rest 21 lumps (35%) were malignant and most were seen in upper inner quadrant, whereas majority of the carcinoma breast were found in upper outer quadrant. Fibroadenoma, seen in the second decade, was most common lesion accounting for 48.3% (29 lesions) and all were diagnosed clinically and on USG and were conrmed on HPE. Breast carcinoma was second common, 35% (21 lesions). Maximum number of Carcinoma breast cases were in 5th and 6th decade, 20 out of 21 (96%). Out of 2 and 4 cases of brocystic disease and phyllodes respectively, one case in each was found to have carcinomatous changes on HPE. Conclusion- Breast lump was the most common presentation in this study for both benign and malignant lesions. Diagnostic accuracy of broadenoma by FNAC and USG is 100% in this study. Diagnostic accuracy of carcinoma breast by FNAC and USG is 90.4% in this study. PPV of overall breast lumps is 96.6% with both FNAC and USG. For carcinoma breast the PPVis 100% with both FNAC AND USG. Lymph node were detected Signicantly by using USG, in a clinically non palpable axillary lymph nodes which helped in the further appropriate management