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Article1 July 1950A CLINICOPATHOLOGIC STUDY OF BRONCHIAL ASTHMA WITH CONSIDERATION OF ITS RELATIONSHIP TO THE "GENERAL ADAPTATION SYNDROME"BERTRAM M. WINER, JOHN F. BEAKEY, MAURICE S. SEGAL, F.A.C.P.BERTRAM M. WINERSearch for more papers by this author, JOHN F. BEAKEYSearch for more papers by this author, MAURICE S. SEGAL, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-1-134 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONBronchial asthma has been a subject of controversy among clinicians and pathologists since the recognition of this disease. Salter,1almost a century ago, stated that ". . . asthma is a disease about whose pathology more various and discrepitant ideas prevail than about any other disease that could be named. . . ." The first major study of the pathology of this disease by Huber and Koessler2in 1922 has been followed by many individual case reports. This literature has recently been reviewed by Rackemann,3Unger4and Gay.5Because of the persistence of varied opinions concerning bronchial asthma, and...Bibliography1. Salter HH: Asthma: its pathology and treatment, 1860, John Churchill, London. Google Scholar2. HuberKoessler HLKK: Pathology of bronchial asthma, Arch. Int. Med. 30: 689-760, 1922. CrossrefGoogle Scholar3. Rackemann FM: Deaths from asthma, J. Allergy 15: 249-258, 1944. CrossrefGoogle Scholar4. Unger L: Pathology of bronchial asthma with five autopsy reports, South. M. J. 38: 513, 1945. CrossrefGoogle Scholar5. Gay LN: The diagnosis and treatment of bronchial asthma, 1946, Williams and Wilkins Co., Baltimore. Google Scholar6. KountzAlexander WBHL: Death from asthma, Arch. Path. 5: 1003, 1928. Google Scholar7. MacDonald IG: Local and constitutional pathology of bronchial asthma, Ann. Int. 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Johns Hopkins Hosp. 47: 338, 1930. Google Scholar31. Selye H: Studies on adaptation, Endocrinology 21: 169-188, 1937. CrossrefGoogle Scholar32. Selye H: General adaptation syndrome and diseases of adaptation, J. Clin. Endocrinol. 6: 117-230, 1946. CrossrefGoogle Scholar33. Rich AR: The rôle of hypersensitivity in periarteritis nodosa as indicated by seven cases developing during serum sickness and sulfonamide therapy, Bull. Johns Hopkins Hosp. 71: 123-140, 1942. Google Scholar34. RichGregory ARJE: The experimental demonstration that periarteritis is a manifestation of hypersensitivity, Bull. Johns Hopkins Hosp. 72: 65-88, 1943. Google Scholar35. Moore RA: A textbook of pathology, 1944, W. B. Saunders Co., Philadelphia. Google Scholar36. Teilum G: Allergic hyperglobulinosis and hyalinosis (paramyloidosis) in the reticuloendothelial system in Boeck's sarcoid and other conditions, Am. J. Path. 24: 389-408, 1948. MedlineGoogle Scholar37. WilsonAlexander KSHL: The relation of periarteritis nodosa to bronchial asthma and other forms of human hypersensitiveness, J. Lab. and Clin. Med. 30: 195-203, 1945. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication November 27, 1948.From the Mallory Institute of Pathology, Boston City Hospital and the Department of Medicine, Tufts College Medical School.Aided by a grant from the U. S. P. H. Service. 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Safety of inhalational therapyAdvances in inhalational therapy in the management of diseases of the chestZur Pathologie des Asthma bronchialeGeneral Practice Review 1 July 1950Volume 33, Issue 1Page: 134-162KeywordsAsthmaHospital medicinePathologists ePublished: 1 December 2008 Issue Published: 1 July 1950 PDF downloadLoading ...

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