Abstract
Intraoral minor salivary glands tumors (MSGT) are uncommon, with geographic variations in frequency and distribution. This study analyzed the clinic-pathologic features of these tumors in Shiraz, southern Iran. All of cases histopathologically recorded as epithelial MSGT in Pathology Department of Khalili Hospital from 2002 to 2009 were evaluated with regard to patient's age and gender, tumor location and type, retrospectively. Out of 82 cases of MSGT, 53.7% were benign and 46.3% were malignant. Pleomorphic adenoma and adenoid cystic carcinoma were the most common benign and malignant tumors, respectively. The palate was the most common site of involvement (64.6%). Male to female ratio was 1:1.27. The mean age of the patients was 35.0±17.2 years for benign and 48.8±18.2 years for malignant tumors. MSGTs in the present study represent many characteristics of other studies. However, our patients who were affected by benign tumors were young.
Highlights
Minor salivary glands are functional structures located in the submucosa of the upper aerodigestive tract.[1]
All of cases histopathologically recorded as epithelial minor salivary glands tumors (MSGT) in Pathology Department of Khalili Hospital from 2002 to 2009 were evaluated with regard to patient's age and gender, tumor location and type, retrospectively
Our patients who were affected by benign tumors were young
Summary
Minor salivary glands are functional structures located in the submucosa of the upper aerodigestive tract.[1] The importance of the lesions lies in the fact that lesions are more likely to be malignant.[2] Studies from other countries report that 13.9-51.4% of all salivary gland tumors (SGTs) arise from an intraoral area and 34.7-67.1% of them are benign.[3,4,5,6] It was shown that incidence of SGTs is influenced by geographic and racial factors.[7,8] Up to now, a large series of MSGTs were reported in Iran. The aim of this study was to determine clinic-pathological features of 82 cases of benign and malignant intraoral MSGT in this region. Intraoral minor salivary glands tumors (MSGT) are uncommon, with geographic variations in frequency and distribution. This study analyzed the clinic-pathologic features of these tumors in Shiraz, southern Iran
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