A clinical study to evaluate the efficacy of Kanchnara Twak Kwatha with Shunthi Churna and Nimba Taila Nasya in Hypothyroidism

Abstract

Context: Hypothyroidism is a clinical syndrome resulting from deficiency of thyroid hormones due to their insufficient synthesis which is turn result in generalized slowing down of metabolic process characterized by broad clinical spectrum ranging from an asymptomatic or subclinical condition to fully manifested clinical condition. It is more common in females than males with middle age women more effected. Materials and Methods: Sixty eligible hypothyroid patients with serum thyroid-stimulating hormone >4.5 μIU/ml and serum T3 and T4 lower than their respective normal range were selected and treated with Kanchnar Twak Kwath with Shunthi Churna and Nimb Taila Nasya for 45 days. Patients were advised to discontinue any medicine they might be taking for the management of hypothyroidism to assess the unbiased effect of therapies. Results: Significant improvement was observed on subjective parameters, and objective parameters. Of the 60 enrolled patients, In group B maximum improvement 62.07%, moderate improvement 20.69%, mild improvement 13.79%, no improvement 3.45%. But in group A maximum improvement 7.14%, moderate improvement 28.57%, mild improvement 42.86%, no improvement 21.43%. after this trial maximum patient had withdrawn their hormone replacement therapy. Conclusion: Kanchnar Twak Kwath with Shunthi Churna and Nimba Taila Nasya are effective in the management of hypothyroidism.