A Clinical Study on the Gynaecological Parameters Pertaining to Polycystic Ovarian Syndrome (PCOS)

Abstract

Background and Aim Polycystic ovarian syndrome PCOS has a major influence on women of reproductive age group resulting in extreme stress at times crippling in nature. This study aimed at evaluating and correlating early signs of PCOS to prevent the future implications.Methods This observational cross-sectional study was conducted between September 2018 and March 2020. Ninety subjects with PCOS based on Rotterdamrsquos criteria were recruited. Details on menstrual history anthropometric measurements infertility spontaneous abortions and acanthosis nigricans were noted and assessed. Excel and Statistical Analysis System SAS version 9.4 software have been used for the analysis. Comparison between two groups and inferential data was evaluated using p-value and 95 CI with Chi-square test.Results The mean age of menarche was 12.97 plusmn 1.17 years. Oligomenorrhea secondary amenorrhea and regular menstrual cycle were observed in 51 56.6 14 15.5 and 25 27.7 subjects respectively. Anthropometric measures of body mass index BMI ge 25 kgm2 waist circumference WC ge 88 cm and hip and waist ndash hip ratio WHR ge 0.85 were observed in 55 61.1 67 74.4 and 86 96.6 subjects respectively. Infertility was observed in 53 58.8 and spontaneous abortions in 24 26.6 subjects. Acanthosis nigricans an indicator of insulin resistance was seen in 61 67.7 subjects which positively correlated with increased BMI and WC.Conclusion Correlation of anthropometric details with insulin resistance infertility and spontaneous abortions can go a long way in preventing the same based on which the pregnancy should be treated as high risk to prevent pregnancy loss and metabolic derangements.