A Clinical Study on the Brain Protection Effect of Propofol Anesthesia on Patients Undergoing Acute Craniocerebral Trauma Surgery Based on Blockchain.

Abstract

In order to explore the effects of propofol anesthesia system based on block chain on brain tissue and brain function protection, 88 patients undergoing craniocerebral trauma surgery are selected for prospective study. The anesthetic dose of propofol during operation in the control group is determined according to general information and personal situation. The team uses blockchain to process the patient's clinical data and general information to calculate the optimal dose of propofol. The changes of hemodynamic indexes of patients in the two groups are compared, including dural incision (T1), 1 h after craniotomy (T2), end of surgery (T3), and 6 h after surgery (T4). The changes of neuron-specific enolase (NSE) and central neuron-specific protein (S100β) at T1, T2, T3, and T4 in 2 groups are observed and recorded. The changes of malondialdehyde (MDA) at T1, T2, T3, and T4 are compared between the two groups. Based on the analysis of clinical data and general information of patients on blockchain, the optimal intraoperative anesthetic dose of propofol for patients can effectively protect the brain function of patients, and the intraoperative anesthesia state is relatively stable, and the changes and improvements of intraoperative indicators are good.