Abstract

Objective To investigate the security and clinical effect of surgical treatment of phacoemulsification and foldable intraocular lens implantation with ciliary groove sutured for lens subluxation in Marfan syndrome.Methods Retrospectively observed clinical data of 14 eyes of 10 cases suffered from Marfan syndrome with significant lens subluxation.The ranges of lens subluxation in all these eyes were more than 90 degree.All eyes were treated in the way that phacoemulsification subluxation lens and implantation of a foldable posterior chamber intraocular lens with ciliary groove sutured.Patients were followed up from 6 to 12 months.The visual acuity,intraocular pressure,intraocular lens situation and complications were recorded.Results All 10 cases (14 eyes) had successful operations.The intraocular inflammatory reaction and pressure were all recovered to normal after therapy.At the last follow-up time,postoperative best corrected distant visual acuity achieved or over preoperative,in which 2 eyes (14.3%) were from 0.05 to 0.2,8 eyes (57.1%) were from 0.25 to 0.5,4 eyes (28.6%) were from 0.6 to 0.8.The intraocular lens was all in the correct situation.There were no severe complications such as corneal endothelial decompensation,subchoroidal hemorrhage,suture exposure,endophthalmitis,secondary glaucoma,retinal detachment and eyeball atrophy and so on.Conclusions The technique of phacoemulsification and foldable intraocular lens implantation with ciliary groove suture is one of the less harmful,safe and efficient therapy for the patients of Marfan syndrome with significant subluxated lens.The further observation is needed for long-term outcome. Key words: Marfan syndrome; Lens subluxation; Phacoemulsification; Posterior chamber IOL; Ciliary groove suture fixation

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