Abstract

Objectives: The main objectives of the present study are to analyze the incidence of papillary carcinoma of the thyroid, study the clinical presentation and behavior of papillary carcinoma of the thyroid, and analyze various surgical modalities of the treatment of papillary carcinoma of the thyroid. Methods: It is a prospective study. A proforma for the study of all papillary carcinoma of thyroid patients was used. The presentation, clinical findings, investigations, and management line were documented. The study was conducted during the period December 2016–November 2018. A total of 50 cases of papillary carcinoma of thyroid in GIMSR-Visakhapatnam were selected based on simple random sampling techniques were clinically evaluated. Results: Among the 66 cases reported with different thyroid types of carcinoma, papillary thyroid cancer constitutes 75%. The results showed that 76% of cases occurred between the age group of 21–50 years. The incidence of female to male ratio was 3.2:1. In 62% of cases, goiter was the most presenting symptom and 92%of patients were euthyroid at the time of presentation. Conclusion: The incidence of papillary thyroid carcinoma in the present study is 75%, following the results of the previous studies. The most common mode of clinical presentation was thyroid swelling which was lower than those in a comparative study. The proportion of different histopathological types of papillary thyroid cancer was similar to those reported in the literature. The most common complication was transient hypoparathyroidism which resolved with calcium supplementation.

Highlights

  • The most common endocrine malignancy in thyroid cancer leads to many deaths due to endocrine cancers

  • The study consists of 50 cases of proven papillary thyroid carcinoma who were admitted in various surgical wards in GIMSR, Visakhapatnam

  • The present study found that the common age group of papillary carcinoma thyroid is 31–40 years

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Summary

Introduction

The most common endocrine malignancy in thyroid cancer leads to many deaths due to endocrine cancers. Most patients have differentiated thyroid cancer (ex-papillary carcinoma thyroid and follicular carcinoma thyroid). Differentiated thyroid carcinoma is commonly seen in young adults with a 2:1 female to male ratio. Thyroid cancer shows different histological entities [1,2] with different clinical behavior. They are well-differentiated malignancies, anaplastic, medullary thyroid, and other unusual cancers such as lymphoma and sarcoma. Papillary carcinoma is good [1,2] and anaplastic carcinoma is worse [1,2]. Even though most thyroid nodules are benign, some may harbor malignancy. Accurate clinical examination, pre-operative workup, and evaluation are needed for appropriate management

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