A CLINICAL STUDY OF NEONATAL SEPTICEMIA CONDUCTED IN KURNOOL MEDICAL COLLEGE/GOVT.GENERAL HOSPITAL,KURNOOL

Abstract

Neonatal septicemia is a major cause of morbidity and mortality in new born infants. To study theOBJECTIVES: incidence,predisposing factors,clinical prole,outcome. The study was conductedMATERIALS AND METHODS: over a period of November-2017-february 2019 ,50 neonates who are showing well documented signs are included in this study,blood investigations like hb,tc,dc with band neutrophil ratio,peripheral smear,micro esr,crp,blood culture,csf,urine,pus,rectal swab will be subjected to c&s and radiological investigations when indicated. culture was bacteriologically positive in 34% cases. ciprooxacin had maximumRESULTS: sensitivity of 88.2%.Leucopenia< 5000/cmm had sensitivity of 47%,specicity of 66.67% and PPA of 42.11%,toxic granulation had 70.56 sensitivity,63.65%specicity and 50%PPA.B/N>0.2 had 88.2%sensitivity 62.4%PPA. m-ESR had sensitivity of 70.56%,specicity of 84.84%,PPA of 70.5%, C-reactive protein had 88.2 sensitivity and 87.8% specicity and 78.95%PPA ,case fatality rate was 28% C O N C L U S I O N : C l i n i c a l f e a t u r e s o f n e o n a t a l s e p t i c a e m i a a r e n o n s p e c i  c a n d v a g u e . s e p s i s s c r e e n h a s g o o d sensitivity,specicity,PPA.combination of tests increase the specicity and PPA. As an individual test C-reactive protein has highest sensitivity.