A clinical study of effects of tamsulosin in ureteric stent related morbidity

Abstract

Background: Most of the Ureteric surgery involves DJ stent Insertion to prevent post operative ureter related morbidity of the patients. This study aims towards the role of tamsulosin in relieving DJ stent related symptoms. Methods: Prospective study conducted between June 2018 to October 2020 in 58 patients randomised by random-number chart into two groups, group A (Non tamsulosin) group B (Tamsulosin). The international prostate symptom score (IPSS) questionnaire and quality of life (QoL) was assessed on admission as a baseline before patient underwent the surgery and reassessed when the patient came for stent removal. Results: The mean age of patients in group A (non-tamsulosin) was 39.38 years with range of 20 to 60 years. The mean age of patients in group B (tamsulosin) was 38.55 with range of 20 to 68 years. In group A consisted of 16 men and 13 women whereas group B had 13 men and 16 women. On comparing non tamsulosin and tamsulosin group, patients in which stent is removed at or <28 post operative day, mean IPSS+QoL component of questionnaire score is 14.1 (SD 3.8) and 11.8 (SD 4.1) respectively. While on comparing non tamsulosin and tamsulosin group, patients in which stent removed after 28th post operative day, mean IPSS+QoL component of questionnaire score is 18.9 (SD 1.0) and 6.4 (SD 1.1) respectively. Conclusions: Oral administration of tablet Tamsulosin 0.4 mg once a daily before sleep at night improves DJ stent related morbid symptoms.