A clinical study of duodenal ulcer perforation

Abstract

Background: Time trends in the epidemiology of perforated peptic ulcer disease reflect complex, multifactorial etiologies. Based on today’s fast and instant life style it is evident that the epidemiology of peptic ulcer disease largely reflects environmental factors, primarily Helicobacter pylori infection, NSAID use, and smoking . Methods: Surgery was defined as urgent less as 4 hours between admission and surgery, same day (4-24 hours) and delayed at a later time during the same admission. This study comprises of 60 cases of duodenal ulcer perforation admitted in the Department of Surgery, Tertiary care Hospital. Operative details included the site and nature of operation performed. Results: Highest incidence was found in 40 – 49 years of age (25%) followed by 20 – 29 years (21.67%), 30 – 39 years (20%), and 50 – 59 years (15%) . Conclusions: Duodenal ulcer perforation was more common in the age group of 40-49 years.