A clinical study of dengue fever cases: NRI Medical College, Chinakakani, Andhra Pradesh, South India

Kakarlathota Kanugolu Muralimohan,Bungabhaskara Rao,Aparanji Gopidi,Chikkala Raghuram,Dhulipalla Dharmateja,Shirisha Gunnam

doi:10.4103/2230-8598.165984

Kakarlathota Kanugolu Muralimohan, Bungabhaskara Rao + Show 4 more

Open Access

https://doi.org/10.4103/2230-8598.165984

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Abstract

Background: Admission of dengue fever/dengue hemorrhagic fever cases was on the rise during the monsoon period of 2013 in NRI Hospital and surrounding Districts of Coastal Andhra Pradesh. A number of deaths due to dengue fever were reported in the previous months. Hence, a clinical study of the dengue cases was done in the late monsoon for a period of 3 months since a large number of cases with bleeding manifestations were referred to our Hospital for platelets transfusion from the local hospitals and nursing homes. Aim: A Clinical study of dengue fever cases in the extended monsoon period and to evaluate the need for platelet transfusion in dengue fever cases. Retrospective Observational Study - Results: In the retrospective observational study, the diagnostic serotyping was done using rapid standard diagnostic kits. Eighty-four dengue seropositive were seen of which dengue fever cases were 55, dengue hemorrhagic fever were 27 and dengue shock syndrome were 2 cases only. Totally, 26 cases with dengue hemorrhagic fever whose platelet counts were below 50,000 cells/cu mm, were given random pooled donor platelet concentrates, while two cases of dengue shock syndrome were given single donor platelet concentrates, fresh frozen plasma and whole blood transfusion. Timely platelets transfusions in cases of dengue hemorrhagic fever and dengue shock syndrome helped to prevent severe hemorrhagic complications, and there were no deaths.

Highlights

AIMS AND OBJECTIVES OF THE STUDYThe monsoon period usually lasts from June to September every year in the Indian Peninsula
As NRI Medical College caters to the needs of the coastal districts of Guntur Krishna, Prakasham and Nellore of Andhra Pradesh and Nalgonda of Telangana, vector borne diseases such as malaria, Chikungunya and dengue fever cases were on the rise
The number of dengue fever cases detected were highest in the month of September 2015 and October 2015 and tailed off in November 2013, which coincided with the increased vector activity during the preceding months.[2,3]

Summary

AIMS AND OBJECTIVES OF THE STUDY

The monsoon period usually lasts from June to September every year in the Indian Peninsula. As NRI Medical College caters to the needs of the coastal districts of Guntur Krishna, Prakasham and Nellore of Andhra Pradesh and Nalgonda of Telangana, vector borne diseases such as malaria, Chikungunya and dengue fever cases were on the rise. As per the reports of National Vector Borne Diseases Survey 1996-2006, Andhra Pradesh reported the incidence of 2% of dengue fever cases. Of 197 cases of dengue fever reported, there were 17 deaths.[6] WHO (World Health Organization) bulletin updated as on March 2014, reported 40% of world population are at risk of exposure, nearly 5,000,000 people need hospitalization out of which 2.5% die.[20]. All cases admitted to medical wards of NRI hospital from 1 September to 30 November, 2013 were taken for study that is, the extended monsoon period. The pregnant women and pediatric cases were excluded from the study

MATERIALS AND METHODS

DISCUSSION

Findings

68 NS 36 NS 6 13 NS 16 5 1 23 17 NS NS NS NS NS NS

CONCLUSIONS