Abstract
AN ESTROGENIC PREPARATION that can be administered orally has long been desired. The wish seems to have been fulfilled by the discovery of stilbestrol. Favorable reports of the estrogenie efficiency of this compound are numerous, but a variety of opinions concerning its toxicity have been expressed. During the past year my associates have collaborated with me to observe the effects of stilbestrol administered to 250 patients. We have been interested to test the efficiency, toxicity, optimum dosage and indication for the use of stilbestrol. In order to avoid prejudice each observer selected his own cases, chose the dosage and recorded his results. All other complaints and symptoms of the patients as well as the estrogenic deficiency have been considered and treated concurrently with the stilbestrol therapy. Only the patients who have returned for observation are included in this report, though it might be assumed that many of those who received the medication were sufficiently relieved of their symptoms to...
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