A Clinical Research about Herbal Cosmetics Containing Momordica charntia L. Extracts on the Anti-wrinkle and Whitening Effects

Abstract

Ho-Jun Jung·Eun-Ju Do·Jin-Sang Lee·Hyun-Jin Park·Gyue-Seok Oh·Mi-Ryeo Kim·Il-Do Ha·Yong-Ha Jeong·Seon-Young Jee Objective : The purpose of this clinical research was to investigate the ef fects of herbal cosmetics containing Momordica charntia L. extracts on the anti-wrinkle and whitenin g effects. Methods : A total of 25 subjects who visited Daegu Hanny Oriental Medical Center from November 1st, 2010 to December 31th, 2010 were included in this study. In this stu dy, we observed change of R1, R2, R3, R4, R5 for using products, change of average melanin content and pigme ntal area, analysis results of subjective wrinkle improvement, Analysis results of subjective whitening improveme nt. Statistical analysis was performed by using paired t-test and wilcoxon signed ranks test. Statistical signi ficance was achieved if the probability was less than 5%(p<0.05) Results : Statistically, herbal cosmetics containing Momordica charntia L . extracts showed siginificant effect on change of R1, R2, R3, R4, R5 for using products, change of aver age melanin content and pigmental area, analysis results of subjective wrinkle improvement, Analysis re sults of subjective whitening improvement(p<0.05). And satisfaction after using herbal cosmetics was near good. Conclusions : Considering the above results, we have concluded that herbal co smetics containing Momordica charntia L. extracts have the remarkable effects on the anti-wr inkle and whitening effects. Key words : anti-wrinkle, whitening, herbal cosmetics, Momordica charntia L. extracts