A CLINICAL EVALUATION OF SHIGRUGUGGULU ON LIVER FUNCTION TEST UNDER SPINAL ANAESTHESIA

Abstract

Shigruguggulu is anubhoota yoga of Banar as Hindu University using as analgesic and anti - inflammatory since long time in the Shalya Ward and OPD of the Sir Sunderlal Hosp ital, Banaras Hindu University. Present research work was done on 150 healthy patients. The patients were divided into three Gr oup s. Each Group included 50 patients with age (16 - 60 year s ), height and weight distribution. The patients were posted for primary threading, herniotomy with herniorrhaphy and hemorrhoidectomy, skin gra fting, sentinel tag, tubectomy and abdominal hysterect omy. Group I was pre medicated with two capsules of Shigruguggulu 500 mg (2/3 part of Shigru root bark decoction and 1/3 Shigru root bark choorn a with guggulu) orally at 10 pm and 90 minute before an esthesia an d inj. Glycopyrrolate 0.2 mg IM, 60 minute bef ore anesthesia. Group II was pre medicated with two capsules of Shigruguggulu 500 mg (Shigru root bark decoction with guggulu) orally at 10 pm and 90 minute before an esthesia and inj. Glycopyrrolate 0.2 mg IM , 60 minute before an esthesia. Group III was pre medicated with tab. Diclofenac sodium 50 mg orally 10 pm and 90 minute before an esthesia and inj. Glycopyrrolat e 0.2 mg IM 60 minute before an esthesia. It wa s observed that no alteration in M ean B lood P ressure , respiratory rate, pulse rate, temperature an d l iver function test etc. Post an esthetic sequel, like nausea, vomiting, headache, backache, CNS irritability was observed insignificant in all the three Group s. It means that drug has no any side effect.