Abstract
A Clinical Comparison of Hospitalized Pediatric Patients with Influenza A(H1N1)Pdm09 Virus Infection of the Years 2009/10 and 2012/13
Highlights
Influenza virus infections contribute largely to in-house admissions in German hospitals
Children were younger in the post-pandemic season 2012/13 than 2009/10 (6.5 vs. 2.1 years, p < 0.01) and the hospital length of stay was longer (5.1 vs. 10.8 days, p < 0.01)
Physicians need to focus especially on infants and preschool children, because these patients are at higher risk for severe clinical outcome and prolonged hospital stay
Summary
Influenza virus infections contribute largely to in-house admissions in German hospitals. In the season of 2012/13 we noted an increased occurrence of ARD in our tertiary care Children’s Hospital at the University of Bonn, Germany, and an increased number of in-house admissions with A(H1N1)pdm virus infections. The present study investigated the clinical course of pediatric in patients with A(H1N1)pdm virus infection comparing the season 2012/13 with the pandemic of 2009/10 in our Children’s Hospital, based on clinically tested predictors. The seasonal influenza of 2012/2013 in Germany was unusually severe, leading to higher numbers of hospitalization rates as compared with previous seasons. This trend was even notable in our tertiary care Children’s Hospital at the University of Bonn, Germany
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