A clinical case of ectopic ACTH syndrome: diagnostic difficulties

Abstract

Ectopic adrenocorticotropic hormone (ACTH-ectopic syndrome) secretion is a rare variant of endogenous hypercortisolism. Development of severe complications in various organs, systems and complex differential diagnoses characterizes the complexity of disease. Also, surgical intervention requires rapid, confirmed diagnosis and localisations of tumours. The presented clinical case is a case with multiple comorbidities presented with hypercortisolism complicating the diagnostic process and demonstrates the difficulties in managing patients with this nosology.