A clinical case of diverticular disease in a patient with COVID-19: features of the course against the background of comorbid pathology

Abstract

As a consequence of the global pandemic of the coronavirus disease (COVID‑19), cases of combination of gastroenterological pathology with endocrinopathies, associated with this pandemic, occur sporadically. Therefore, reporting about a unique clinical case of post‑covid comorbidity of these diseases seems to be advisable.
 Patient K., 68 years old, who had been suffering from diabetes insipidus for five years and received appropriate treatment (desmopressin) daily, was hospitalized for 28 days at the lung disease center of the Regional Phthisiopulmonological Center due to a severe course of COVID‑19. Two months after discharge, due to prevailed gastrointestinal complaints (pain in the bowel areas, stool frequency up to 7 times a day, dryness mouth, urination up to 3 times at night (nocturia), general weakness), which required another thorough differential diagnosis, she was hospitalized in the Gastroenterology Department of Regional Clinical Hospital. The diagnosis of severe post‑covid complications has been established, including intestinal diverticular disease and type 2 diabetes mellitus, and patient was transferred to the surgical department.
 The problems of searching and improving methods for early diagnosis of post‑covid conditions that potentiate the development of polymorbidity are urgent. A pathogenetically based approach to the administration of therapy will promote reducing morbidity and mortality in patients with comorbid diseases. The coronavirus pandemic forces the medical and scientific community to join efforts for investigation of new comorbid condition. The timely diagnosis of relatively new and understudied post‑covid diseases should become the main task of multidisciplinary teams of doctors. Investigation of the diversity of the clinical courses, the development and improvement of algorithms for the treatment and prevention of severe complications of diverticular intestinal disease in combination with diabetes insipidus and diabetes mellitus are the important prospects of scientific research.