Abstract
A cine k-edge subtraction imaging system has been constructed for less invasive transvenous angiography research. It utilizes synchrotron radiation and consists of a monochromator, an x-ray television camera with a high-speed shutter, and a data-acquisition and control unit. A 50×60-mm2 monochromatic x ray of about 400 mR/s intensity is produced. The x-ray photon energy is changed by using an oscillating cam mechanism which changes the angle of the crystal with respect to the beam. 16 ms is required to change the photon energy across the k edge for a change up to 800 eV. K-edge subtraction angiography of rats is performed following intravenous injection of materials containing iodine. Dual-energy images are acquired using 17-ms exposures with the same interval. Repetition of this sequence gives a series of k-edge subtraction images. Arteries of 0.3–0.4 mm diam are clearly seen.
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