Abstract

We consider the following repulsive-productive chemotaxis model: find u ≥ 0, the cell density, and v ≥ 0, the chemical concentration, satisfying1∂tu−Δu−∇⋅(u∇v)=0inΩ,t>0,∂tv−Δv+v=upinΩ,t>0,\\documentclass[12pt]{minimal}\t\t\t\t\\usepackage{amsmath}\t\t\t\t\\usepackage{wasysym}\t\t\t\t\\usepackage{amsfonts}\t\t\t\t\\usepackage{amssymb}\t\t\t\t\\usepackage{amsbsy}\t\t\t\t\\usepackage{mathrsfs}\t\t\t\t\\usepackage{upgreek}\t\t\t\t\\setlength{\\oddsidemargin}{-69pt}\t\t\t\t\\begin{document}$$ \\left\\{ \\begin{array}{l} \\partial_t u - {\\Delta} u - \\nabla\\cdot (u\\nabla v)=0 \\ \\ \\text{ in}\\ {\\Omega},\\ t>0,\\\\ \\partial_t v - {\\Delta} v + v = u^p \\ \\ { in}\\ {\\Omega},\\ t>0, \\end{array} \\right. $$\\end{document}with p ∈ (1, 2), {Omega }subseteq mathbb {R}^{d} a bounded domain (d = 1, 2, 3), endowed with non-flux boundary conditions. By using a regularization technique, we prove the existence of global in time weak solutions of (1) which is regular and unique for d = 1, 2. Moreover, we propose two fully discrete Finite Element (FE) nonlinear schemes, the first one defined in the variables (u,v) under structured meshes, and the second one by using the auxiliary variable σ = ∇v and defined in general meshes. We prove some unconditional properties for both schemes, such as mass-conservation, solvability, energy-stability and approximated positivity. Finally, we compare the behavior of these schemes with respect to the classical FE backward Euler scheme throughout several numerical simulations and give some conclusions.

Highlights

  • Chemotaxis is the biological process of the movement of living organisms in response to a chemical stimulus, movement that can be addressed towards a higher or lower concentration of a chemical substance

  • We prove some unconditional properties for both schemes, such as mass-conservation, solvability, energy-stability and approximated positivity

  • From the biological point of view, the nonlinear signal production considered in model (3) is justified and explains the saturation effects of chemotactic signal production at large densities of cells

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Summary

Introduction

Chemotaxis is the biological process of the movement of living organisms in response to a chemical stimulus, movement that can be addressed towards a higher (chemo-attraction) or lower (chemorepulsion) concentration of a chemical substance. In the case of linear ( 1) or quadratic ( 2) production term, problem (3) is well-posed (see [9, 17] respectively) in the following sense: there exist global in time weak solutions in 3 domains, which are regular (and unique) for 1 and 2 domains. Energy-stability of time-discrete numerical approximations and fully discrete FE schemes for a chemorepulsion model with quadratic production have been analyzed in [17] and [18, 19], respectively; while, in the case of linear production, we refer [20]. The positivity of only time-discrete schemes and approximated positivity of a fully discrete FE scheme associated with a chemorepulsion model with quadratic signal production were proved in [17] and [19], respectively; while, for the case of linear production, we refer to [20]. By taking 1 in (6): i.e., In addition, integrating (7) in , one has

Regularized problem
Scheme UV
Approximated positivity of un
Scheme US
Positivity of un
Energy-stability
Experimental convergence rates
Conclusions
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