Abstract

Despite advances in antenatal diagnosis and perinatal care, mortality rate remains elevated in patients with congenital diaphragmatic hernia (CDH). We report a case of left sided CDH in a term baby with persistent gastroesophageal reflux (GER) after repair, and persistent pulmonary hypertension requiring multiple vasodilators. Baby required high frequency oscillatory ventilation for 6 weeks. After failed medical management, bedside gastrostomy in neonatal intensive care unit was done. Nissen’s fundoplication was done later. After 2.5 months child was discharged asymptomatically.

Highlights

  • Congenital diaphragmatic hernia (CDH) is a lifethreatening congenital anomaly with an incidence of 1 in 2,500 live births

  • Gastroesophageal reflux (GER) is a wellrecognized complication in postoperative patients with CDH which may occur in 30–70% of patients [2], but an incidence of up to 80 % has been reported in patients treated with ECMO before CDH repair

  • We report a case of CDH complicated by refractory GERD

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Summary

Introduction

Congenital diaphragmatic hernia (CDH) is a lifethreatening congenital anomaly with an incidence of 1 in 2,500 live births. Few studies focused on associated chronic morbidity and long-term outcomes.[1] Gastroesophageal reflux (GER) is a wellrecognized complication in postoperative patients with CDH which may occur in 30–70% of patients [2], but an incidence of up to 80 % has been reported in patients treated with ECMO (extracorporeal membrane oxygenation) before CDH repair. It is reported that 21-60% of CDH patients remain symptomatic after medical treatment, and require anti-reflux surgery.[3] we report a case of CDH complicated by refractory GERD.

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