Abstract
Tissue plasminogen activator (t-PA) is the only approved thrombolytic therapy for the treatment of stroke patients. Its effectiveness is highly time dependent due to the sensitivity of brain tissue to ischemia. Therefore, it is crucial to minimize the time between the onset of symptoms and the initiation of an effective thrombolytic treatment. Here we describe a case that received an ultrarapid thrombolytic therapy. A 72-year-old woman was presented at our emergency department with a sudden occurrence of severe left sided hemiparesis. After exclusion of intracranial hemorrhage, the patient received intravenous thrombolysis therapy 7 min after arrival at our hospital. The patient showed a fast, nearly complete improvement of symptoms, and a minor infarction was detected in a follow up MRI. We describe this case and the general stroke management in our emergency department that led to this rapid door-to-needle time.
Highlights
Stroke is the second most frequent cause of death worldwide, accounting for ~11% of the total deaths
This time can be divided in the time between onset of symptoms and the arrival at an emergency department and the time between arrival the application of thrombolytic therapy
We describe a case with a door-to-needle-time of 7 minutes along with the general stroke management in our emergency department that led to this rapid door-to-needle time
Summary
Stroke is the second most frequent cause of death worldwide, accounting for ~11% of the total deaths. In order to optimize the door-to-needle-time, the development of a standardized protocol for stroke management is strongly suggested [7]. The peek performance (minmal door-to-needle-time) might be a valueable parameter for the effectiveness of an implemented stroke management.
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