Abstract
Plasma cell neoplasms involve excessive immunoglobulin (Ig) secretion which is the main culprit. Hence, they are the most sought after cells in bone marrow whenever plasma cell dyscrasias is suspected. In their absence, the diagnosis becomes questionable. However, if one can identify those Igs disguising themselves as crystals in histiocytes, the path becomes clearer. We present one such case of pancytopenia where an incidental finding of these crystal storing histiocytes helped clinch the diagnosis of a monoclonal gammopathy which was otherwise suspected to be a consequence of anti-tuberculous therapy.
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