Abstract
The antibiotic medicines were widely applied for therapy use or prevention of flu infection. The residual antibiotic medicine might be present in wastewater and sludge during the manufacturing processes, and it is liable to intentionally release to the surroundings to harm to the environment or threaten human health. This study selected a carbapenem antibiotic manufacturing plant as case study to investigate the feasibility of antibiotic wastewater treatment by an MBR system. The characteristics of imipenem antibiotic wastewater showed the average concentrations of 3929 mg L−1 COD and 2383 mg L−1 BOD. The characteristics of cilastatin antibiotic wastewater showed the average concentrations of 4245 mg L−1 COD and 1760 mg L−1 BOD. The combined antibiotic wastewater was treated by an MBR system, and the treatment efficiencies are 92.5% for BOD removal, 96.0% for COD removal and 81.5% for suspended solid removal. The inflow wastewater of the MBR system contains 4.97 ng L−1 imipenem and 3.77 ng L−1 cilastatin, and the outflow concentrations through MBR treatment are ND for imipenem and 0.02 ng L−1 for cilastatin. The treatment efficiencies of antibiotic wastewater are more than 99.9% through MBR treatment.
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