Abstract

PurposeSoft tissue deformation severely impacts the registration of pre- and intra-operative image data during computer-assisted navigation in laparoscopic liver surgery. However, quantifying the impact of target surface size, surface orientation, and mesh quality on non-rigid registration performance remains an open research question. This paper aims to uncover how these affect volume-to-surface registration performance.MethodsTo find such evidence, we design three experiments that are evaluated using a three-step pipeline: (1) volume-to-surface registration using the physics-based shape matching method or PBSM, (2) voxelization of the deformed surface to a 1024^3 voxel grid, and (3) computation of similarity (e.g., mutual information), distance (i.e., Hausdorff distance), and classical metrics (i.e., mean squared error or MSE).ResultsUsing the Hausdorff distance, we report a statistical significance for the different partial surfaces. We found that removing non-manifold geometry and noise improved registration performance, and a target surface size of only 16.5% was necessary.ConclusionBy investigating three different factors and improving registration results, we defined a generalizable evaluation pipeline and automatic post-processing strategies that were deemed helpful. All source code, reference data, models, and evaluation results are openly available for download: https://github.com/ghattab/EvalPBSM/.

Highlights

  • In laparoscopic liver surgery, haptic perception is missing and it is more difficult to localize a tumor

  • We evaluate the effect of each factor on registration performance, by designing three experiments and an evaluation pipeline

  • We found a significant difference when using different target surface sizes, as the null hypothesis was rejected with a p value or P = 2e−16

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Summary

Introduction

Haptic perception is missing and it is more difficult to localize a tumor. Displaying information about target or risk structures such as the tumor or intrahepatic vessels and bile ducts can be very helpful Providing such information in navigation, i.e., intra-operative image guidance, could assist the surgeon during the interven-. International Journal of Computer Assisted Radiology and Surgery (2020) 15:1235–1245 the intra-operative image data, e.g., from a stereo-endoscope, are employed to reconstruct an intra-operative surface of the visible hepatic tissue This liver surface is aligned to the preoperative model. As the liver tissue deforms under pressure exerted by surgical instruments (i.e., manipulation), or nonlinear forces exerted by breathing motion, or other organs (e.g., the heart), an important task is tracking surface changes and registering them This aspect integrates soft tissue registration continuously and refers to dynamic registration. It is a prerequisite for real-time navigation systems

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