A CASE SERIES ON MENINGIOMA BASED ON WHO GRADING SYSTEM

Abstract

Background:The dura mater, arachnoid mater and pia mater are layers of meninges surrounding brain and spinal cord. Meningiomas are tumors arising from them.These are heterogeneous group of tumors and are have 14 distinct histologic types and 03 grades of malignancy.We have studied the variants of meningiomas, as early detection helps in the treatment and improves quality of life. Objectives: -Study the histological types as per WHO grading system 2016 for meningiomas. -Differentiate the benign and malignant meningiomas on histopathology. Methods: The study is carried out in the department of pathology, D.Y. Patil medical college and hospital kolhapur from June 2020 to June 2021. Total 19 intracranial tumors were received. Sections were stained with H&E and IHC was done wherever necessary. Results:We had total 19 patients with tumors in different locations of brain. Mainly parasagital followed by intradural . Age range was 32 to 70 years with female predominance. Common histological subtypes were meningothelial (5 cases) and fibrous (5 cases), followed by transitional and angiomatous (2 cases each) and psamomatous (1 case) - WHO grade I tumors. Clear cell and atypical - grade II. Papillary, anaplastic variant - grade III. Conclusion: Meningiomas are slow growing tumors arising from the meningothelial cells. Commonly they are benign WHO grade I with female predominance. Early detection helps in the treatment and improves quality of life.