Abstract
Epidemic dropsy (ED) occurs because of intoxication with alkaloid sanguinarine of Argemone Mexicana, the Prickly Poppy. Here we report a case series of ten patients, belonging to the same family, residents of a northern district in Uttar Pradesh, India. All of these admitted in June 2018 with pallor and erythematous bilateral pedal edema. Our aim to report all these cases is to create awareness among people and to tell the importance of this malady, although it is illegal to sell mustard oil un-bottled in our country India.  
Highlights
1 INTRODUCTION: In India mustard oil is used as edible oil, as a result Epidemic dropsy (ED) generally occurs in these regions where this oil is regularly used[1].Oedema was formerly known as Dropsy, or hydropsy
Sanguinarine and dihydrosanguinarine are the quaternary ammonium salts found in alkaloid benzyl isoquinolone of Argemone oil which is the main culprit of pathogenesis of epidemic dropsy
2 CASE PRESENTATION: This case series of epidemic dropsy occurred in a northern district of Uttar Pradesh India, in a poor family with involvement of total ten family members
Summary
In India mustard oil is used as edible oil, as a result Epidemic dropsy (ED) generally occurs in these regions where this oil is regularly used[1].Oedema was formerly known as Dropsy, or hydropsy. Sanguinarine and dihydrosanguinarine are the quaternary ammonium salts found in alkaloid benzyl isoquinolone of Argemone (katkar) oil which is the main culprit of pathogenesis of epidemic dropsy. These two major alkaloids cause dilatation of blood vessels, proliferation and increased vascular wall permeability. These mechanisms are responsible for oedema as a result of leakage of protein-rich plasma from intravascular to the extracellular region. This oedema initially starts in bilateral lower limbs [1].
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