Abstract

Introduction: Ovarian-cancer is the 3rd mostcommon cancer in Indian-women, accounting for 3% of all malignancies and 6% of deaths from cancer. It is 5th most-common cause of death from malignancy in women.1 Case-presentation: This is a cases-series of 4 cases Case 1 62 year, postmenopausal-woman with abdominalpain and ultrasound report of 109x82x87mm rightovarian-simple-cyst of (410cc), Ca-125 -> 8.50, posted for Laparotomy. A 15x 10cm right- ovarian-cyst removed. Frozen-section -> benign. Histopathology-> serous-cystadenoma Case 2 43-year, nulligravida. With pain-abdomen, posted for laparoscopic-cholecystectomy for gall-bladderpolyp with intraoperative findings of bulky-ovaries with ascitic-fluid showing malignant-cells , Ca-125 -> 66 , ultrasound s/o enlarged (7.6x6.4 cm) right-ovary, .Posted for exploratory-Laparotomy .Bulky irregularovaries removed. Frozen-section ->granulosa-cell tumour, Histopathology-metastatic adenocarcinoma / malignant sex-cord-stromal tumour. Case 3 70-year-old, COVID-19-positive patient referred for ovarian-torsion, with Ca125 - 8.7. Ultrasound -> 66x55 mm left adnexal-cyst with torsion; Posted for leftovariotomy + right-salpingoophorectomy. A 7x7cm left-sided-haemorrhagic-ovarian-Cyst removed. Histopathology -> serous-cystadenofibroma.Case 4 67-year-old postmenopausal-woman with painabdomen, Ca-125-154, ultrasound showing 14 x 7.5cm right-ovarian-complex-cyst, posted for Exploratorylaparotomy, a 15x15 cm twisted-right-ovarianhaemorrhagic cyst removed. Frozen-section->benign Histopathology ->Rt ovary- serous-cystadenoma + torsion Discussion: Ovarian cancer has nonspecificsymptoms resembling those of less serious conditions. Eg. Pain-abdomen. Staging-laparotomy with frozen-section remains the preferred approach for ovarian-tumors. Conclusion: In my case-series 3/4 women were postmenopausal, all presented with vague symptoms of pain-abdomen. Frozen-section may not be conclusive in every case, hence staging-laparotomy is ideal modality of management.

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