Abstract

BackgroundThe World Health Organization’s and Centers for Disease Control and Prevention’s definition of Zika infection are symptoms of fever, rash, joint pain, myalgia, headache and conjunctivitis. The diagnosis of Zika infection is based on the clinical history, physical examination and laboratory investigations which includes blood and urine Zika virus Polymerase Chain Reaction.Case presentationTwo patients presented with atypical presentation of Zika infection to Sengkang Health, Alexandra Hospital during the recent Zika outbreak in Singapore in August 2016.Madam A presented with isolated generalized rash with no fever, joint pain, myalgia, headache or conjunctivitis.Mr. B presented with isolated fever of 39.4 °C with no rash, joint pain, myalgia, headache or conjunctivitis.Both patients’ blood Zika Polymerase Chain Reactions were positive at the time of presentation.ConclusionThe described case reports illustrated the challenges that our community Family Physicians faced in diagnosing patients infected with Zika virus. Coupled with the knowledge that most patients are asymptomatic, Family Physicians need to have a high index of clinical suspicion for early identification of patients infected with Zika virus, so as to institute timely treatment and appropriate measures to mitigate the outbreak of Zika infection in the community. Appropriate epidemiological measures such as ensuring prompt and thorough contact tracing of the cases are instrumental in the control of this public health problem.

Highlights

  • The World Health Organization’s and Centers for Disease Control and Prevention’s definition of Zika infection are symptoms of fever, rash, joint pain, myalgia, headache and conjunctivitis

  • The described case reports illustrated the challenges that our community Family Physicians faced in diagnosing patients infected with Zika virus

  • Coupled with the knowledge that most patients are asymptomatic, Family Physicians need to have a high index of clinical suspicion for early identification of patients infected with Zika virus, so as to institute timely treatment and appropriate measures to mitigate the outbreak of Zika infection in the community

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Summary

Conclusion

The described case reports illustrated the challenges that our community Family Physicians faced in diagnosing patients infected with Zika virus. Coupled with the knowledge that most patients are asymptomatic, Family Physicians need to have a high index of clinical suspicion for early identification of patients infected with Zika virus, institute treatment and measures to reduce the outbreak of Zika infection in the community. Physicians play an important role at the Primary Healthcare level in educating the public that vector control remains key to reducing the spread of the Zika virus. Residents should undertake vector control measures regularly to ensure proper housekeeping within their premises at all times and remove any potential mosquito breeding habitats. More field reports of the presentation of the disease will be necessary to develop a more robust definition of this disease, especially within the South East Asia Region.

Background

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