Abstract

Background: Anti-glomerular basement membrane (GBM) antibody disease is a rare autoimmune condition causing rapidly progressive glomerulonephritis, typically affecting adults. We present an unusual case of anti-GBM nephritis in a 7-year-old child, initially identified through a routine school urine screening. This young patient displayed no overt signs of renal impairment but testing revealed the atypical presence of GBM antibodies.. Objective: The purpose of this case report is to draw attention to the uncommon occurrence of anti-GBM disease in pediatric populations presenting with normal renal function. Diagnosis and management in such cases poses challenges given our understanding of anti-GBM nephritis derives mainly from adult patients. This anomaly prompts consideration of alternate screening and treatment approaches for younger patients who may manifest the disease atypically compared to older populations. Study design: A Case Report Study. Place and duration of study: department of nephrology at the MiangulAbdul Haq Jahanzeb Kidney Hospital From January 2021 to July 2021 Methods: This Case Report study was conducted in the department of nephrology at the MiangulAbdul Haq Jahanzeb Kidney Hospital From January 2021 to July 2021 after ethical clearance for hospital administration of this study. Results: (anti-GBM) illness in infants with intact renal function is uncommon. For this reason, professionals must carefully pick an appropriate therapy for youngsters since the prognosis is grim. Conclusion: Figures 1 to 3 show that things are true of (anti-GBM) illness. (anti-GBM) infection was suspected eventhough her kidneys were in good shape. A VUR might have caused this with a bladder issue as a secondary conditionsource. As an (anti-GBM) medication, DFPP works well for those with normal renal function. Keywords: Anti-GBM, Pediatrics, Normal renal function, School urine screening programmed, case report

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