Abstract

Von Willebrand disease (VWD) is the most common inherited bleeding disorder caused by a deficiency in von Willebrand factor (VWF), which can be either quantitative or qualitative. There are three types of VWD, with Type III being the rarest but most severe form. In pregnant women, VWD can pose life-threatening risks during labor and the early postpartum period. At present, there is no curative treatment for this disorder, so management focuses on early diagnosis and minimizing blood loss. We present the case of a 28-year-old female diagnosed with VWD during her first pregnancy. While her prenatal period was uneventful, she experienced complications postpartum following an instrumental vaginal delivery. However, with a collaborative effort from a multidisciplinary team, both the mother and baby had favorable outcomes. Timely diagnosis, initiation of prepartum and intrapartum VWF and, clotting factor replacement therapy, careful monitoring of postpartum bleeding, and consistent follow-up are crucial to enhance recovery and prevent complications.

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