Abstract
AbstractMalformations of cortical development are rarely diagnosed in utero. Cortical malformations are aberrations in the process of corticogenesis. We report two rare and unique cases of evolving cortical malformation with unusual ultrasonogram markers: (1) narrow cavum septum pellucidum and (2) ill-defined and irregular lateral ventricular borders on the midtrimester anomaly scan. This was further confirmed by fetal brain evaluation on magnetic resonance imaging with additional information on irregular ventricular borders, scattered hyperintensities in the cerebral parenchyma and periventricular area, loss of cerebral layering pattern at 24 weeks gestation in one case, and hemimegalencephaly in another case with a probable diagnosis of evolving cortical malformation. Literature review reveals the above as an unusual presentation on the anomaly scan.
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