A case report on clinical feature, cause and outcome in male pediatric child with cerebral palsy with corpus callosum agenesis with mycosis

Abstract

Introduction : The most prevalent developmental issue impacting children’s function is cerebral palsy. Brain damage or insult during pregnancy, perinatal, or postnatal periods causes a static, nonprogressive disease. The corpus callosum connects the left and right hemispheres of the brain and is one of the disorders that affect the agenesis of the corpus callosum. The corpus callosum is either absent or substantially absent in ACC. A disruption in brain cell migration during foetal development causes it. Mucormycosis is the third most frequent invasive fungal infection in children, according to recent studies, and its prevalence is increasing. Present complaints and Investigation : A 12-year-old male boy was presented to the hospital with oedema around his eyes, a fever that had been present for three days, respiratory distress, and altered sensorium. He had a history of developmental delay and cerebral palsy. Corpus callosal agenesis is visible on MRI and CT scans of the brain. The lesions have shifted the right orbital muscles. Right eye proptosis is evident. The main diagnosis, therapeutic intervention and outcomes : The doctor diagnosed a case of cerebral palsy with corpus callosal agenesis, retroorbital oedema, and mycosis after a physical examination and inquiry. Vancomycin, MgSO4, and other pharmacological treatments were administered intravenously. For four days, the patient was on CPAP. She received every treatment, but the prognosis was dismal. Her signs and symptoms of respiratory distress were decreased. Conclusion : The thickness of the mid-body of the corpus callosum correlates with the volume of cerebral white matter in children with cerebral palsy and developmental delay, regardless of gestational age or neuromotor outcome.