A case report of ultrasonographic findings in bilateral diffuse Uveal melanocytic proliferation

Jingli Guo,Qing Chang,Wei Liu,Gezhi Xu,Wenyi Tang,Wenji Wang,Min Zhou,Qian Chen,Chunhui Jiang

doi:10.1186/s12886-020-01720-6

Abstract

BackgroundTo report undescribed characteristics of patients with bilateral diffuse uveal melanocytic proliferation (BDUMP) on ultrasound biomicroscopy (UBM) and high-frequency B-scan ultrasonography.Case presentationTwo of four participants presented with worsening bilateral vision after previously diagnosed primary pulmonary or ovarian carcinoma. The other two patients were diagnosed with lung carcinoma after presentation with BDUMP. All patients had ciliary body nevi-like lesion in combination with iris or ciliary body cysts, and uveal thickening on UBM. Focally elevated choroidal nevi-like lesion and exudative retinal detachment with choroidal thickening were detected with B-scan ultrasonography.ConclusionsOur case series demonstrates the uveal characteristics of patients with BDUMP based on high-frequency B-scan ultrasonography and UBM. Ultrasonographic findings are crucial in the diagnosis of BDUMP because it is occult in nature.

Highlights

To report undescribed characteristics of patients with bilateral diffuse uveal melanocytic proliferation (BDUMP) on ultrasound biomicroscopy (UBM) and high-frequency B-scan ultrasonography.Case presentation: Two of four participants presented with worsening bilateral vision after previously diagnosed primary pulmonary or ovarian carcinoma
Our case series demonstrates the uveal characteristics of patients with BDUMP based on highfrequency B-scan ultrasonography and UBM
Ultrasonographic findings are crucial in the diagnosis of BDUMP because it is occult in nature

Summary

Conclusions

Our case series demonstrates the uveal characteristics of patients with BDUMP based on highfrequency B-scan ultrasonography and UBM. Ultrasonographic findings are crucial in the diagnosis of BDUMP because it is occult in nature. Keywords: Bilateral diffuse uveal melanocytic proliferation, Ultrasound biomicroscopy, High-frequency B-scan ultrasonography, Ciliary body nevi

Background

Discussion and conclusion