Abstract

Basal cell carcinoma (BCC) is the most frequently occurring malignant periocular tumor. The aim of treatment remains surgery with negative margins. We report a case of 65-year-old woman who was diagnosed with BCC of internal canthus of the right eye, in October 2011. The patient was treated by surgical resection in 2 steps with reconstruction by a frontal flap. The treatment resulted in complete remission without any recurrence after ten years of surgery.

Highlights

  • Basal cell carcinoma (BCC) is the most frequent skin cancer in the world and accounts for 90% of all tumors on the eyelid with a slight male preponderance [1, 2]

  • We report a case of 65-year-old woman who was diagnosed with BCC of internal canthus of the right eye, in October 2011

  • The best treatment option for BCC is surgery, including Mohs Micrographic Surgery (MMS) and wide surgical excision in order to reduce the risk of local recurrence and it remains the goal of treatment

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Summary

Introduction

Basal cell carcinoma (BCC) is the most frequent skin cancer in the world and accounts for 90% of all tumors on the eyelid with a slight male preponderance [1, 2]. The incidence of orbital invasion is nearly 2-4%, and risk factors include large lesion size, multiple recurrences, aggressive histological subtype, internal canthus location, and advanced patient age [5]. The best treatment option for BCC is surgery, including Mohs Micrographic Surgery (MMS) and wide surgical excision in order to reduce the risk of local recurrence and it remains the goal of treatment. A biopsy for histological analysis was performed and confirmed the diagnosis of sclerodermiform type basal cell carcinoma of the internal canthus of the right eye (Figure 2). Initial therapy was surgical resection, and the patient was treated with 2 steps by ophthalmologist and plastic surgeon: In the first time: a large carcinological excision with 1.5cm of safety margin and reconstruction of the loss of latero-nasal substance and internal canthus by a frontal flap (Figure 3). The patient had no recurrence of her disease with complete clinical remission after ten years of complete surgical excision

Discussion
Surgery
Radiotherapy
Vismodegib
Chemotherapy
Findings
Conclusion
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