Abstract
Infectious mononucleosis is an acute illness due to Epstein Barr virus infection, which occurs commonly in young adults. Liver involvement in acute EBV infection occurs in up to 95% of patients between the 6th and 15th day of illness and is usually mild [1]. Here we report on a 7-year-old girl treated by Gastroenterology, Hepatology, and Nutrition Unit of Al-Adan Hospital pediatric Department, presented with prolonged fever, lymphadenopathy, generalized edema, hyperbilurubi- nemia and elevated liver enzymes secondary to EBV infection. This case represents a rare presentation of common viral infection in pediatric population.
Highlights
Epstein-Barr virus (EBV) infection typically causes the clinical syndrome of infectious mononucleosis
Hepatitis with mild transient elevations in serum aminotransferases is often reported in Epstein-Barr virus (EBV) infectious mononucleosis
Patient was treated as a case of pyrexia from unknown origin (PUO) and covered with Intravenous broad spectrum antibiotics, but with no improvement in her symptoms
Summary
Epstein-Barr virus (EBV) infection typically causes the clinical syndrome of infectious mononucleosis. Liver involvement is usually mild, and resolves spontaneously [2]. Hepatitis with mild transient elevations in serum aminotransferases is often reported in Epstein-Barr virus (EBV) infectious mononucleosis. Mild jaundice develops in approximately 5% of cases and may result from cholestasis or virus-induced hemolysis [3]. The majority of patients recover without apparent sequelae and most patients will need only supportive treatment
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