Abstract
A 52-year-old woman was admitted because of dysphagia and an oppressive feeling in the chest. Chest X-ray, esophagogram, esophagoscopy, EUS, CT, MRI, bronchoscopy and bronchial artery angiography findings led to a diagnosis of middle to posterior mediastinal tumor (bronchogenic cyst). At surgery, a mass originating in the muscle coat of the esophagus was identified and successfully removed along with a part of the esophageal mucosa. The resected specimen was a solid mass and 7×5×5cm in size. Microscopically, the tumor was composed of spindle cells in irregular fascicles, reminiscent of Antoni A type tissue. Immunohistochemically, tumor cells were positive for S-100 protein staining but negative for muscle specific actin (HHF35) staining and desmin staining. The final diagnosis was neurinoma of the esophagus. Neurinoma of the esophagus is an extremely rare disease. To our knowledge, this is the seventh case of neurinoma of the esophagus reported in the Japanese literature.
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