A Case Report of Isolated Left Ventricular Non-Compaction Presenting with Congestive Heart Failure and Intramural Thrombus

Laxmi Narayan Goit,Shaning Yang

doi:10.4236/ym.2019.31007

Abstract

Isolated left ventricular non-compaction is recently described as a rare form of cardiomyopathy that is associated with a heart failure, life threatening cardiac arrhythmia and thromboembolic complications. The diagnosis is based on echocardiography demonstration of spongy myocardium. Here we report a case of 74 years old female patient diagnosed as an isolated left ventricular non-compaction with congestive heart failure, intramural thrombus and hypertension. There is no specific treatment for LVNC; therapeutic measures are directed towards the patient’s symptom (heart failure, arrhythmia and thrombotic events) and consideration of an implantable cardioverter defibrillator and cardiac transplantation.

Highlights

Left ventricle non-compaction (LVNC) is a recently described cardiomyopathy which is often familial and autosomal dominant and characterized by presence of excessively prominent trabeculations and deep intertrabecular recesses [1] [2]
Isolated left ventricular non-compaction is recently described as a rare form of cardiomyopathy that is associated with a heart failure, life threatening cardiac arrhythmia and thromboembolic complications
Clinical manifestations can range from no symptom to progressive deterioration in cardiac function such as congestive heart failure seen in 30% - 70% of cases, systemic thromboembolic event occurring in 7% - 38%, and stroke [4]

Summary

Introduction

Left ventricle non-compaction (LVNC) is a recently described cardiomyopathy which is often familial and autosomal dominant and characterized by presence of excessively prominent trabeculations and deep intertrabecular recesses [1] [2]. Both familial and sporadic forms of non-compaction have been described, the prevalence being estimated to be between 0.01% - 0.27% [3]. Cardiac arrhythmias can occur including ventricular and supraventricular tachycardia as well as atrial fibrillation. These disorders can lead to syncope and sudden cardiac death in up to 18% of the patients in observed populations [5]. Cardiac Magnetic Resonances Imaging is the best imaging modality for the diagnosis of non-compaction of ventricle and gives detail information regarding the extent of non-compaction and supplemental morphological information [6]

Case Presentation

Discussion

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Learning Point

Conclusion